The early diagnosis of congenital hypothyroidism is vital in the prevention of prenatal injury. The objective of this investigation was to show the results reached with this new strategy of diagnosis from its inception in our country in 1986, with the implementation of the national program for early detection, and beginning later in our province in 1990. From that time until May of 2000, it managed to diagnose and treat 39 patients, thereby satisfying the main objective of the program. A clinical study was carried out for all patients considering the parameters established by the program at the national level, and the subjects were evaluated at birth by determining the stimulating hormone of the thyroid gland (TSH) in umbilical cord blood samples by means of a technique called UMELISA TSH using an ultra-microanalysis system (EXTREME). The collected data was processed using a Pentium III microchip, through an SPSS statistical processor. The results: the tirotropine in the umbilical cord blood samples showed numbers higher than 96 mU/l in 72% of the cases. A 23% showed a rank from 40 mU/l to 96 mU/I. Only 5% of the cases had values lower than 40 mU/l. The elapsed time between the birth and the diagnosis was less than a month in the 56.4%. A 36 % of the patients were collected between a month and two months. Only in the 7.6 % of the cases the elapsed time was greater than two months. The evolutionary determination of the plasmatic tirotropine during the investigation expressed its lower values with a dose of sodic levotiroxin at 13-15 µg/kg/day, and the group evaluated over the course of five years, following the guidelines established by the program, showed normal levels of tirotropine and did not present disturbs in the growth and psychomotor development.