Multiresistance to antibiotics and alternatives to solve this crisis

Abstract

Increasingly, conventional antibiotics are less effective against pathogenic bacteria and fungi, because strategies have been selected in these microorganisms that prevent various antibiotics from being able to harm them. Therefore, the search and development of new effective drugs against these multiresistant microorganisms is essential for human health. There are many natural products from different living organisms, which have historically been used as antibiotics. Some of these are home remedies to fight against microbial infections in different cultures throughout human history. In this article, we will explain the phenomenon of multidrug resistance by microorganisms. Additionally, in one hand, we will discuss traditional and modern alternatives that have potential use in the prevention and treatment of infectious diseases. On the other hand, we will talk about the latest approaches that have been implemented by modern medicine to combat the problem of multiresistance.